{"id":1519,"date":"2024-07-07T17:02:45","date_gmt":"2024-07-07T17:02:45","guid":{"rendered":"https:\/\/pemaejetes.org.al\/?p=1519"},"modified":"2024-07-07T17:02:47","modified_gmt":"2024-07-07T17:02:47","slug":"zbulime-te-reja-per-riparimin-e-mielines-cvl-1001-dhe-cvl-2001","status":"publish","type":"post","link":"https:\/\/pemaejetes.org.al\/index.php\/2024\/07\/07\/zbulime-te-reja-per-riparimin-e-mielines-cvl-1001-dhe-cvl-2001\/","title":{"rendered":"Zbulime t\u00eb reja p\u00ebr riparimin e mielin\u00ebs, CVL-1001 dhe CVL-2001"},"content":{"rendered":"\n

Hyrje
Skleroza Multiple (SM) \u00ebsht\u00eb nj\u00eb s\u00ebmundje q\u00eb prek miliona njer\u00ebz n\u00eb mbar\u00eb bot\u00ebn, duke shkaktuar d\u00ebmtime n\u00eb sistemin nervor. P\u00ebr ata q\u00eb jetojn\u00eb me SM, \u00e7do p\u00ebrparim n\u00eb trajtimin e s\u00ebmundjes \u00ebsht\u00eb nj\u00eb shpres\u00eb e re.<\/p>\n\n\n\n

Convelo Therapeutics po zhvillon dy ila\u00e7e premtuese, CVL-1001 dhe CVL-2001, q\u00eb mund t\u00eb ndihmojn\u00eb n\u00eb riparimin e d\u00ebmtimit t\u00eb mielin\u00ebs\u2014substanca q\u00eb mbulon dhe mbron fibrat nervore.<\/p>\n\n\n\n

Si Funksionojn\u00eb K\u00ebto Ila\u00e7e?
CVL-1001 dhe CVL-2001 synojn\u00eb t\u00eb ndihmojn\u00eb qelizat n\u00eb trurin dhe palc\u00ebn kurrizore t\u00eb prodhojn\u00eb dhe riparojn\u00eb mielin\u00ebn. K\u00ebto ila\u00e7e veprojn\u00eb duke inhibuar disa proteina specifike q\u00eb pengojn\u00eb procesin e riparimit t\u00eb mielin\u00ebs. Duke b\u00ebr\u00eb k\u00ebt\u00eb, ila\u00e7et nxisin diferencimin e qelizave oligodendrocite, t\u00eb cilat jan\u00eb p\u00ebrgjegj\u00ebse p\u00ebr prodhimin e mielin\u00ebs.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Rezultatet Paraklinike
N\u00eb testet laboratorike dhe n\u00eb modele t\u00eb kafsh\u00ebve, CVL-1001 dhe CVL-2001 kan\u00eb treguar rezultate shum\u00eb premtuese. Ila\u00e7et kan\u00eb arritur t\u00eb rrisin riparimin e mielin\u00ebs me rreth 50% n\u00eb modelet e brejt\u00ebsve, nj\u00eb arritje q\u00eb sugjeron se mund t\u00eb ndihmojn\u00eb n\u00eb uljen e simptomave t\u00eb SM-s\u00eb.<\/p>\n\n\n\n

Hapat e Radh\u00ebs n\u00eb Zhvillim
Aktualisht, Convelo Therapeutics po kryen studime sigurie n\u00eb kafsh\u00eb p\u00ebr t\u00eb siguruar q\u00eb ila\u00e7et jan\u00eb t\u00eb sigurta p\u00ebr p\u00ebrdorim njer\u00ebzor. Pas p\u00ebrfundimit t\u00eb k\u00ebtyre studimeve, kompania planifikon t\u00eb filloj\u00eb provat klinike tek njer\u00ebzit. K\u00ebto prova jan\u00eb t\u00eb nevojshme p\u00ebr t\u00eb siguruar se ila\u00e7et jan\u00eb t\u00eb efektshme dhe t\u00eb sigurta p\u00ebr pacient\u00ebt me SM.<\/p>\n\n\n\n

Kur mund t\u00eb jen\u00eb disponib\u00ebl?
N\u00ebse gjith\u00e7ka shkon sipas planit, provat klinike mund t\u00eb fillojn\u00eb s\u00eb shpejti dhe do t\u00eb zgjasin disa vite. N\u00ebse rezultatet jan\u00eb pozitive dhe ila\u00e7et marrin miratimin rregullator, CVL-1001 dhe CVL-2001 mund t\u00eb jen\u00eb n\u00eb treg brenda 5-7 viteve t\u00eb ardhshme.<\/p>\n\n\n\n

P\u00ebrfundim
CVL-1001 dhe CVL-2001 jan\u00eb dy ila\u00e7e q\u00eb ofrojn\u00eb shpres\u00eb t\u00eb re p\u00ebr trajtimin e Skleroz\u00ebs Multiple. Nd\u00ebrsa ende jan\u00eb n\u00eb fazat e hershme t\u00eb zhvillimit, rezultatet e deritanishme jan\u00eb shum\u00eb inkurajuese. P\u00ebrparimi n\u00eb k\u00ebto trajtime mund t\u00eb sjell\u00eb nj\u00eb p\u00ebrmir\u00ebsim t\u00eb madh n\u00eb jet\u00ebn e pacient\u00ebve me SM.<\/p>\n\n\n\n

Fondacioni Pema e Jet\u00ebs \u00ebsht\u00eb nj\u00eb organizat\u00eb jo fitimprur\u00ebse q\u00eb mb\u00ebshtet pacient\u00ebt me SM n\u00eb Shqip\u00ebri. N\u00ebp\u00ebrmjet p\u00ebrpjekjeve t\u00eb tyre, ata ofrojn\u00eb ndihm\u00eb dhe mb\u00ebshtetje p\u00ebr t\u00eb p\u00ebrmir\u00ebsuar cil\u00ebsin\u00eb e jet\u00ebs s\u00eb individ\u00ebve t\u00eb prekur nga kjo s\u00ebmundje. <\/p>\n\n\n\n

\"\"<\/figure>\n","protected":false},"excerpt":{"rendered":"

P\u00ebrparimet m\u00eb t\u00eb fundit p\u00ebr medikamentet p\u00ebr personat q\u00eb vuajn\u00eb nga skleroza multiple. K\u00ebto ila\u00e7e jan\u00eb nj\u00eb shpres\u00eb p\u00ebr riparimin e mielin\u00ebs, nj\u00eb nga sfidat m\u00eb t\u00eb m\u00ebdha.<\/p>\n","protected":false},"author":2,"featured_media":1526,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[49,10],"tags":[],"class_list":["post-1519","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-semundjet-kronike","category-skleroza-multiple"],"acf":[],"yoast_head":"\nZbulime t\u00eb reja p\u00ebr riparimin e mielin\u00ebs, CVL-1001 dhe CVL-2001 - Pema e Jetes<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pemaejetes.org.al\/index.php\/2024\/07\/07\/zbulime-te-reja-per-riparimin-e-mielines-cvl-1001-dhe-cvl-2001\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Zbulime t\u00eb reja p\u00ebr riparimin e mielin\u00ebs, CVL-1001 dhe CVL-2001 - Pema e Jetes\" \/>\n<meta property=\"og:description\" content=\"P\u00ebrparimet m\u00eb t\u00eb fundit p\u00ebr medikamentet p\u00ebr personat q\u00eb vuajn\u00eb nga skleroza multiple. 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